Periodontics, Oral Surgery & Implants

Abstract: Platelet concentrates for surgical use are innovative tools of regenerative medicine, and were widely tested in oral and maxillofacial surgery. Unfortunately, the literature on the topic is contradictory and the published data are difficult to sort and interpret. In periodontology and dentoalveolar surgery, the literature is particularly dense about…
We recently read an article in OOOOE about platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in human cell cultures,1 and that article raised significant questions regarding methodology and conclusions. Because Dr. Gassling was not able to clarify his methodology when we contacted him, we think it is important to share…

Safety Issues Associated With Platelet-Rich Fibrin Method

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Published: Wednesday, 20 May 2015 14:48 Written by
In a recent series of articles1-5 in the March 2006 issue of OOOOE, Dohan et al. describe a new autologous “platelet-rich fibrin concentrate (PRF): a secondgeneration platelet concentrate.” On page e47, a “10-mL glass-coated plastic” blood collection tube islisted as an integral part of blood collection kit supplied by the…
We recently read with a great interest an article published in OOOOE, where He et al.1 tried to compare the effects in vitro on the proliferation and differentiation of rat osteoblasts induced by a platelet-rich plasma (PR) and a platelet-rich fibrin (PRF). We have a significant experience with cell cultures…

Letters to the Editor

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Published: Wednesday, 06 May 2015 14:31 Written by
Re: Clinical Evaluation of a Modified Coronally Advanced Flap Alone or in Combination With a Platelet- Rich Fibrin Membrane for the Treatment of Adjacent Multiple Gingival Recessions: A 6-Month Study. Aroca S, Keglevich T, Barbieri B, Gera I, Etienne D. (J Periodontol 2009;80:244-252). Choukroun’s Platelet-Rich Fibrin Membranes in Periodontal Surgery:…
Dental implants are commonly used in daily practice; however, most surgeons do not really know the characteristics of these biomedical devices they are placing in their patients. The objective of this work is to describe the chemical andmorphological characteristics of 14 implant surfaces available on the market and to establish…
Choukroun Platelet-Rich Fibrin (PRF) can be considered an autologous healing biomaterial, incorporating leukocytes, platelets and a wide range of key healing proteins within a dense fibrin matrix.

Growth-promoting action and growth factor release by different platelet derivatives

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Published: Wednesday, 15 April 2015 13:56 Written by
Abstract: Platelet derivatives are commonly used in wound healing and tissue regeneration. Different procedures of platelet preparation may differentially affect growth factor release and cell growth. Preparation of platelet-rich fibrin (PRF) is accompanied by release of growth factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and transforming…

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